I see this all the time… E-stops on Hazardous Materials process located at the point of the expected/intended failure point, such as a loading/unloading station. Many safety pros have experience with E-stops as a safety device for machinery/equipment, in which the E-stop is located at the point of potential entrapment inside the machine/equipment. Even ANSI requires this location.
However, in Process Safety, we do NOT want these activation devices located at the possible failure location. We want them REMOTE from these locations. This is because when the unloading/loading hose fails and creates a hazardous environment, we do not want the worker or driver to have to enter that hazardous environment to shut down the loading/unloading process safely; we want them to exit the area!
It is a 180-degree flip from machinery/equipment E-Stop thinking. REMOTE ACTIVATION is built into many RAGAGEPs involving hazardous materials. Check out NFPA 58, CGA 2.1, IFC Chapter 50, etc.