The IRSST just published a method of measuring nanoparticles penetration through protective gloves. With the exponential growth in industrial applications of nanotechnologies and the corresponding increased risk of occupational exposure to nanomaterials, adoption of the precautionary principle is advisable. To apply this principle, personal protective equipment against nanoparticles must be made available, even though it should be regarded only as a last line of defence in an overall risk control strategy. In an effort to address the current lack of tools and knowledge in this area, the IRSST developed a method to measure the penetration of nanoparticles through protective glove materials under conditions simulating workplace use.